Global Statistics

All countries
177,816,485
Confirmed
Updated on June 17, 2021 5:25 am
All countries
160,602,622
Recovered
Updated on June 17, 2021 5:25 am
All countries
3,848,938
Deaths
Updated on June 17, 2021 5:25 am

Global Statistics

All countries
177,816,485
Confirmed
Updated on June 17, 2021 5:25 am
All countries
160,602,622
Recovered
Updated on June 17, 2021 5:25 am
All countries
3,848,938
Deaths
Updated on June 17, 2021 5:25 am

Scientists discover key brain enzyme controlling sexual desire in males

Grand Jury Deliberations in Breonna Taylor Case Will Be Released

U.S.|Grand Juror in Breonna Taylor Case Says Deliberations Were MisrepresentedThe Kentucky attorney general’s office said it would release the panel’s recordings after a grand juror contended in a court filing that its discussions were inaccurately characterized.Breonna Taylor's family and the lawyer Ben Crump, right, said the charges a Kentucky grand jury agreed upon in the…

Video shows alleged ballot harvesting in Ilhan Omar’s district

Fox News Back to Top ©2020 FOX News Network, LLC. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed. All market data delayed 20 minutes. New Privacy Policy - New Terms of Use (What's New) - FAQ

A Once-in-a-Century Climate ‘Anomaly’ Might Have Made World War I Even Deadlier

(John Finney Photography/Moment/Getty Images) An abnormally bad season of weather may have had a significant impact on the death toll from both World War I and the 1918 Spanish flu pandemic, according to new research, with many more lives being lost due to torrential rain and plummeting temperatures. Through a detailed analysis of an ice…

Sean Hannity claims Dems ‘put all their eggs in the debate basket’ ahead of first Biden-Trump showdown

Joe Biden's campaign has "put all their eggs in the debate basket" after the Democratic nominee kept a low profile for much of the summer, Sean Hannity claimed Monday.“I believe his campaign team – they are seeing what we all see,” said the “Hannity” host, who noted that the former vice president's campaign wrapped up its public events…

Tucker: Amy Coney Barrett ‘represents everything that made this a great country,’ so Dems ‘despise her’

Supreme Court nominee Judge Amy Coney Barrett is causing an uproar among Democrats and according to Tucker Carlson, her happy family is what’s driving them crazy.“Democrats know Amy Coney Barrett’s life refutes the lies they have pushed on the rest of us for decades, [so] they must destroy her personally,” the “Tucker Carlson Tonight” host said…

Researchers have discovered the location of male sexual desire in specific regions of brain tissue where an important enzyme called aromatase is present.

Although scientists have investigated aromatase, they do not yet understand the full functions of this enzyme in the adult brain.

In a recent study in mice, a team of researchers at Northwestern Medicine in Chicago, IL, and the Frederick National Laboratory for Cancer Research, MD, uncovered more detail about this enzyme’s actions in the adult brain.

The findings appear in the journal Endocrinology.

In the brain, aromatase transforms testosterone, a hormone that drives sexual activity in males, into estradiol, which is a type of estrogen.

Scientists have shown that estrogens are important for the control of reproductive function in both sexes. In addition, estrogens are critical for functional and organizational roles in brain development and adult behavior.

To determine whether brain aromatase is essential for normal male sexual activity, the Northwestern researchers developed mice that lacked aromatase in the brain.

In these male mice, sexual activity was reduced by approximately 50%. This decrease in activity occurred even in the presence of strikingly higher levels of testosterone in their blood compared with the control group of male mice. Mice that could not produce aromatase in any area of the body, including the brain, showed no sexual activity at all.

“Male mice partially lost interest in sex,” states study author Dr. Hong Zhao, research associate professor in obstetrics and gynecology at Northwestern University Feinberg School of Medicine.

Dr. Zhao further emphasizes the key role of aromatase in the production of estrogen. “Estrogen has functions in males and females. Testosterone has to be converted to estrogen to drive sexual desire in males,” she explains.

Senior author Dr. Serdar Bulun, chair of obstetrics and gynecology at the Feinberg School of Medicine and Northwestern Medicine, explains vividly how a male mouse would usually react in the company of a female mouse:

“It would chase after her and try to have sex with her.”

However, Dr. Bulun notes: “If you knock out the aromatase gene in the brain, their sexual activity is significantly reduced. There is less frequency of mating. The male mice are not that interested.”

He concludes: “This is the first key finding to explain how testosterone stimulates sexual desire.”

“[F]or the first time, we demonstrated conclusively that the conversion of testosterone to estrogen in the brain is critical to maintain full sexual activity or desire in males. Aromatase drives that.”

– Dr. Serdar Bulun

The study authors believe that their findings suggest that “sexual behavior may be modified though inhibition or enhancement of brain aromatase enzyme activity.” This knowledge could potentially lead to new treatments for disorders of sexual desire.

According to the scientists, it is possible to use drugs to target aromatase to control the sexual desires of a male.

For example, hypoactive sexual desire disorder, more commonly known as low sexual desire, is a common condition.

Low sexual desire is a common side effect of many widely used medications, including a group of antidepressants called selective serotonin reuptake inhibitors (SSRIs).

The team states that a treatment focused on increasing aromatase might boost sexual desire in those who experience this side effect.

On the other hand, doctors can also treat hypersexuality disorder, or compulsive sexual desire, using an existing aromatase inhibitor. However, a side effect of this treatment is osteoporosis, a type of bone disease in which bones become weak and may break.

The researchers hope that the results of the new study will help guide the development of new selective drugs that block only the brain promoter region of aromatase.

If scientists could achieve this specificity, the medications would not cause some of the unpleasant side effects of existing aromatase inhibitors.

Read More

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Hot Topics

Grand Jury Deliberations in Breonna Taylor Case Will Be Released

U.S.|Grand Juror in Breonna Taylor Case Says Deliberations Were MisrepresentedThe Kentucky attorney general’s office said it would release the panel’s recordings after a grand juror contended in a court filing that its discussions were inaccurately characterized.Breonna Taylor's family and the lawyer Ben Crump, right, said the charges a Kentucky grand jury agreed upon in the…

Video shows alleged ballot harvesting in Ilhan Omar’s district

Fox News Back to Top ©2020 FOX News Network, LLC. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed. All market data delayed 20 minutes. New Privacy Policy - New Terms of Use (What's New) - FAQ

A Once-in-a-Century Climate ‘Anomaly’ Might Have Made World War I Even Deadlier

(John Finney Photography/Moment/Getty Images) An abnormally bad season of weather may have had a significant impact on the death toll from both World War I and the 1918 Spanish flu pandemic, according to new research, with many more lives being lost due to torrential rain and plummeting temperatures. Through a detailed analysis of an ice…

Sean Hannity claims Dems ‘put all their eggs in the debate basket’ ahead of first Biden-Trump showdown

Joe Biden's campaign has "put all their eggs in the debate basket" after the Democratic nominee kept a low profile for much of the summer, Sean Hannity claimed Monday.“I believe his campaign team – they are seeing what we all see,” said the “Hannity” host, who noted that the former vice president's campaign wrapped up its public events…

Tucker: Amy Coney Barrett ‘represents everything that made this a great country,’ so Dems ‘despise her’

Supreme Court nominee Judge Amy Coney Barrett is causing an uproar among Democrats and according to Tucker Carlson, her happy family is what’s driving them crazy.“Democrats know Amy Coney Barrett’s life refutes the lies they have pushed on the rest of us for decades, [so] they must destroy her personally,” the “Tucker Carlson Tonight” host said…

Related Articles

Grand Jury Deliberations in Breonna Taylor Case Will Be Released

U.S.|Grand Juror in Breonna Taylor Case Says Deliberations Were MisrepresentedThe Kentucky attorney general’s office said it would release the panel’s recordings after a grand juror contended in a court filing that its discussions were inaccurately characterized.Breonna Taylor's family and the lawyer Ben Crump, right, said the charges a Kentucky grand jury agreed upon in the…

Video shows alleged ballot harvesting in Ilhan Omar’s district

Fox News Back to Top ©2020 FOX News Network, LLC. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed. All market data delayed 20 minutes. New Privacy Policy - New Terms of Use (What's New) - FAQ

A Once-in-a-Century Climate ‘Anomaly’ Might Have Made World War I Even Deadlier

(John Finney Photography/Moment/Getty Images) An abnormally bad season of weather may have had a significant impact on the death toll from both World War I and the 1918 Spanish flu pandemic, according to new research, with many more lives being lost due to torrential rain and plummeting temperatures. Through a detailed analysis of an ice…