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Shortage Archives - Virus Reports https://virusreports.net/tag/shortage/ Mon, 21 Sep 2020 19:21:03 +0000 en-US hourly 1 https://wordpress.org/?v=6.7.7 https://s3.us-west-1.wasabisys.com/virusreports/2020/05/cropped-virus-favicon-32x32.png Shortage Archives - Virus Reports https://virusreports.net/tag/shortage/ 32 32 T cell shortage linked to severe COVID-19 in elderly; antiseptic spray may limit virus spread https://virusreports.net/t-cell-shortage-linked-to-severe-covid-19-in-elderly-antiseptic-spray-may-limit-virus-spread/ https://virusreports.net/t-cell-shortage-linked-to-severe-covid-19-in-elderly-antiseptic-spray-may-limit-virus-spread/#respond Mon, 21 Sep 2020 19:21:03 +0000 https://virusreports.net/t-cell-shortage-linked-to-severe-covid-19-in-elderly-antiseptic-spray-may-limit-virus-spread/ WASHINGTON (Reuters) — The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.A lower supply of a certain type of immune cell in older people that is critical to fighting foreign invaders may help…

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WASHINGTON (Reuters) — The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

A lower supply of a certain type of immune cell in older people that is critical to fighting foreign invaders may help explain their vulnerability to severe COVID-19, scientists say. When germs enter the body, the initial “innate” immune response generates inflammation not specifically targeted at the bacteria or virus.

Within days, the more precise “adaptive” immune response starts generating antibodies against the invader along with T cells that either assist in antibody production or seek out and attack infected cells.

In a small study published on Wednesday in Cell, COVID-19 patients with milder disease had better adaptive immune responses, and in particular, stronger T-cell responses to the coronavirus.

People over age 65 were much more likely to have poor T cell responses, and a poorly coordinated immune response in general, coauthor Shane Crotty of the La Jolla Institute for Immunology said in a news release.

As we age, our supply of “naive” T cells shrinks, he explained. Put another way, we have fewer “inexperienced” T cells available to be activated to respond to a new invader. “Ageing and scarcity of naive T cells may be linked risk factors for failure to generate a coordinated adaptive immune response, resulting in increased susceptibility to severe COVID-19,” the researchers said.

An antiseptic nasal spray containing povidone-iodine may help curb transmission of the new coronavirus, preliminary research suggests.

In test tube experiments, a team of ear, nose and throat doctors found that a povidone-iodine nasal spray inactivated the virus in as little as 15 seconds. The nasal spray they tested is typically used to disinfect the inside of the nose before surgery. Formulations designed for use on skin are not safe in the nose, the researchers note.

They reported on Thursday in JAMA Otolaryngology – Head and Neck Surgery that they now have their patients use the spray before intranasal procedures, to reduce the risk of virus transmission through the air via droplets and aerosol spread.

They also suggest instructing patients to perform nasal decontamination before coming to appointments, to “further decrease intranasal viral load and … prevent spread in waiting areas and other common areas.” They caution, however, that routine use of povidone-iodine would not be safe for some people, including pregnant women and patients with thyroid conditions. Larger clinical trials have not yet proved that viral transmission is curbed by intranasal povidone-iodine solutions, but “these studies are already underway,” the researchers said.

Some COVID-19 antibody tests are much more reliable than others. But even with the best ones, reliability varies among patient subgroups, a new study suggests. Some tests look for IgM or IgA antibodies, the first antibodies produced by the immune system in response to an invader, which do not remain long in the body.

Other tests – the most common kind – look for IgG antibodies, which generally develop within seven to 10 days after symptoms begin and remain in the blood for some time after the patient recovers.

In a study posted on medRxiv on Wednesday in advance of peer review, researchers analyzed data from 11,809 individuals whose COVID-19 had been diagnosed with highly rated tests to see how well the various antibody assays would “recall” that the patient had been infected.

The most commonly used assays, which look for IgG, had a 91.2% recall rate. But the IgA and IgM assays had estimated recall rates of 20.6% and 27.3%, respectively, coauthor Natalie Sheils of UnitedHealth Group told Reuters. “Recall varies significantly across subpopulations and according to timing of the tests, with performance becoming relatively stable after day 14,” she said. “The tests performed better for men versus women, for non-whites versus whites and for individuals above age 45.” More research is needed to understand why these variations occur, Sheils added.

Click here for a Reuter’s graphic on vaccines and treatments in development.

(Reporting by Nancy Lapid; Editing by Bill Berkrot)

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US ‘likely’ to see shortage of pharmaceutical drugs if coronavirus outbreak continues, intelligence report finds https://virusreports.net/us-likely-to-see-shortage-of-pharmaceutical-drugs-if-coronavirus-outbreak-continues-intelligence-report-finds/ https://virusreports.net/us-likely-to-see-shortage-of-pharmaceutical-drugs-if-coronavirus-outbreak-continues-intelligence-report-finds/#respond Sat, 27 Jun 2020 19:20:58 +0000 https://virusreports.net/us-likely-to-see-shortage-of-pharmaceutical-drugs-if-coronavirus-outbreak-continues-intelligence-report-finds/ A decrease in generic drugs would hurt low-income and unemployed Americans.June 27, 2020, 2:04 PM6 min read With coronavirus outbreaks continuing to spread across the world, the United States is "likely" to see a shortage of generic pharmaceutical drugs, according to a new federal intelligence report obtained by ABC News. The report, prepared by the…

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A decrease in generic drugs would hurt low-income and unemployed Americans.

June 27, 2020, 2:04 PM

6 min read

With coronavirus outbreaks continuing to spread across the world, the United States is “likely” to see a shortage of generic pharmaceutical drugs, according to a new federal intelligence report obtained by ABC News.

The report, prepared by the Department of Homeland Security and distributed Thursday to law enforcement and government agencies around the country, warned that the U.S. is already seeing shortages of more than 200 drugs and medical supplies due to strains on the supply chain caused by international shutdowns early on in the pandemic.

Those shortages would only be made worse should unchecked outbreaks force yet another round of widespread shutdowns, the analysts concluded, further straining the system in a way that many U.S.-based pharmaceutical companies would be “unable to quickly offset.”

“Chinese factories that produce raw ingredients for common antibiotics closed for weeks as of March and India’s lockdown extended until the end of May,” the report said, citing news reports. “France, Germany, and China have also considered re-imposing lockdown measures as COVID-19 cases have begun to re-emerge.”

The warning comes as officials in some states have already halted some reopening plans or closed back down as coronavirus cases rise in at least 29 states, according to an ABC News analysis. Florida reported just under 9,000 new cases on Friday, the highest number since the start of the pandemic.

Dr. Anthony Fauci, the nation’s top infectious disease official, made what he called a “plea” to the country on Friday to understand that the outbreaks, which are mainly in the South and West, could potentially spread to the entire country.

“If we don’t extinguish the outbreak, sooner or later, even ones that are doing well are going to be vulnerable to the spread,” Fauci said. “So we need to take that into account because we are all in it together, and the only way we’re going to end it is by ending it together.”

Vice President Mike Pence, however, said the country has made “truly remarkable progress” in moving forward and commended “all 50 states in this country are opening up safely and responsibly” before acknowledging some increases.

Dr. Jay Bhatt, former medical chief at the American Hospital Association, called the report “extremely concerning” — especially in the middle of a pandemic.

“Accessing affordable generic medications for vulnerable populations can mean the difference between a good outcome and a bad outcome,” said Bhatt, an ABC News contributor. “As infections and hospitalizations rise, our patients can’t endure shortages from lifesaving medications. We have to apply our lessons from several months ago so we don’t end up in dire straits.”

The report further warned drug shortages would have a disproportionate effect on low-income Americans.

A decrease in generic pharmaceuticals, which are significantly less expensive than their brand-name counterparts, would “most risk the health of low-income and unemployed Americans,” who have already been hard hit by the economic hardships of the pandemic, the report found.

“Individuals who cannot afford generic pharmaceuticals are unlikely to switch to brand-name prescriptions because they can cost as much as 95 percent more,” the report said, citing data from a U.S. pharmaceutical research company and a Food and Drug Administration study.

“I am worried about underserved communities and safety net hospitals without significant resources in urban and rural communities as well,” Bhatt said. “I hope hospitals and states not facing shortages can share with those that are to meet the need.”


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How A Shortage Of Sand Could Delay A Coronavirus Vaccine l FiveThirtyEight https://virusreports.net/how-a-shortage-of-sand-could-delay-a-coronavirus-vaccine-l-fivethirtyeight/ https://virusreports.net/how-a-shortage-of-sand-could-delay-a-coronavirus-vaccine-l-fivethirtyeight/#respond Wed, 22 Apr 2020 12:21:10 +0000 https://virusreports.net/how-a-shortage-of-sand-could-delay-a-coronavirus-vaccine-l-fivethirtyeight/ As laboratories across the globe scramble to make a coronavirus vaccine, manufacturers face shortages of common ingredients and supplies. FiveThirtyEight's Senior Science Writer, Maggie Koerth, explores the unexpected shortages that could delay a vaccine for COVID-19.Read more from Maggie: https://fivethirtyeight.com/features/...Website: http://fivethirtyeight.com/Twitter: http://twitter.com/fivethirtyeight/ Facebook: https://www.facebook.com/fivethirtyei... Podcast: https://itunes.apple.com/us/podcast/f...Merch: http://fivethirtyeight.com/store

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As laboratories across the globe scramble to make a coronavirus vaccine, manufacturers face shortages of common ingredients and supplies. FiveThirtyEight’s Senior Science Writer, Maggie Koerth, explores the unexpected shortages that could delay a vaccine for COVID-19.

Read more from Maggie: https://fivethirtyeight.com/features/…

Website: http://fivethirtyeight.com/
Twitter: http://twitter.com/fivethirtyeight/
Facebook: https://www.facebook.com/fivethirtyei…
Podcast: https://itunes.apple.com/us/podcast/f…
Merch: http://fivethirtyeight.com/store

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Hospitals deal with lack of dialysis devices amid coronavirus crisis https://virusreports.net/hospitals-deal-with-lack-of-dialysis-devices-amid-coronavirus-crisis/ https://virusreports.net/hospitals-deal-with-lack-of-dialysis-devices-amid-coronavirus-crisis/#respond Sun, 19 Apr 2020 15:25:17 +0000 https://virusreports.net/hospitals-deal-with-lack-of-dialysis-devices-amid-coronavirus-crisis/ Fox News Back to Top ©2020 FOX News Network, LLC. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed. All market data delayed 20 minutes. New Privacy Policy - New Terms of Use (What's New) - FAQ

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A Lack Is Looming, But Rather of Ventilators, Now It’s Dialysis Machines https://virusreports.net/a-lack-is-looming-but-rather-of-ventilators-now-its-dialysis-machines/ https://virusreports.net/a-lack-is-looming-but-rather-of-ventilators-now-its-dialysis-machines/#respond Sat, 18 Apr 2020 08:22:58 +0000 https://virusreports.net/a-lack-is-looming-but-rather-of-ventilators-now-its-dialysis-machines/ After weeks of searching high and low for ventilators, Governor Andrew Cuomo and health care leaders around the state are breathing a little easier—and sending some of the frantically acquired units to New Jersey, where they’re increasingly needed during the coronavirus pandemic.But now, many hospital workers on the front lines in the metro area have…

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” We just have nine or 10 devices, and now we have over 30 patients that require them,” said one doctor who manages an intensive care system in Queens but who wasn’t authorized to speak.

The term “rationing” is activating for political leaders, health officials, and hospital executives, however the Queens and Brooklyn doctors unapproved to speak both said they already are, in impact, allocating dialysis care.

Fishbane, from Northwell Health, said at his largely suburban healthcare facility network when clients on ventilators aren’t getting better– possibly they have other issues like dementia or metastatic cancer, however perhaps they don’t–” that leads to concerns about need to dialysis be supplied,” when their kidneys start to fail.

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