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https://s3.us-west-1.wasabisys.com/virusreports/2020/05/cropped-virus-favicon-32x32.png Sanofi Archives - Virus Reports https://virusreports.net/tag/sanofi/ 32 32 Sanofi Stops Supplying Hydroxychloroquine to COVID-19 Patients in Clinical Trials https://virusreports.net/sanofi-stops-supplying-hydroxychloroquine-to-covid-19-patients-in-clinical-trials/ https://virusreports.net/sanofi-stops-supplying-hydroxychloroquine-to-covid-19-patients-in-clinical-trials/#respond Sat, 30 May 2020 17:21:07 +0000 https://virusreports.net/sanofi-stops-supplying-hydroxychloroquine-to-covid-19-patients-in-clinical-trials/ The malaria drug is quickly falling out of favor with the medical community as a potential treatment for the disease. On the back of mounting concerns about hydroxychloroquine's safety, global pharmaceutical major Sanofi (NASDAQ:SNY) has quit providing it to COVID-19 patients enrolled in its clinical trials for the drug. It has also put a temporary…

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The malaria drug is quickly falling out of favor with the medical community as a potential treatment for the disease.

Eric Volkman

On the back of mounting concerns about hydroxychloroquine’s safety, global pharmaceutical major Sanofi (NASDAQ:SNY) has quit providing it to COVID-19 patients enrolled in its clinical trials for the drug. It has also put a temporary halt on recruiting new subjects for the research.

Hydroxychloroquine, originally designed to treat malaria, was formerly considered a potential treatment for COVID-19, the disease that can result from the SARS-CoV-2 coronavirus. It had some high-level support, most notably from President Donald Trump, who at one point claimed he was regularly taking it.

A coronavirus colony.

Image source: Getty Images.

The pharmaceutical giant’s decision follows the World Health Organization’s (WHO’s) stoppage of its own clinical trials on hydroxychloroquine and the subsequent banning of the drug’s use by several European countries. The source of its concern is a recent paper published in U.K. medical journal The Lancet, indicating increased death rates from taking the medication.

That paper, which is based on an analysis of medical records, is not the only research that has found the drug might not be appropriate for COVID-19 patients. Last month, a similar analysis of 368 U.S. veterans also indicated elevated death rates in patients receiving the treatment.

Two randomized, controlled clinical trials were being conducted by Sanofi to test hydroxychloroquine’s efficacy in fighting COVID-19. One was a multinational study involving 210 patients presenting an early stage of the disease. These individuals had not been hospitalized. The other, larger one involved roughly 300 people suffering from moderate to severe forms of the disease who had been hospitalized; this was limited to Europe.

On Friday, shares of Sanofi inched up by 0.9%, roughly in line with the performance of the wider stock market on the day.


Eric Volkman has no position in any of the stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.

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Sanofi suspends recruitment for coronavirus clinical trials testing hydroxychloroquine https://virusreports.net/sanofi-suspends-recruitment-for-coronavirus-clinical-trials-testing-hydroxychloroquine/ https://virusreports.net/sanofi-suspends-recruitment-for-coronavirus-clinical-trials-testing-hydroxychloroquine/#respond Fri, 29 May 2020 19:21:00 +0000 https://virusreports.net/sanofi-suspends-recruitment-for-coronavirus-clinical-trials-testing-hydroxychloroquine/ A box of Plaquenil, an anti-malaria drug hydroxychloroquine made by Sanofi, used for years to treat malaria and autoimmune disorders.Alain Pitton | NurPhoto | Getty ImagesFrench drugmaker Sanofi said Friday it is suspending recruitment of new patients for its clinical trials looking at anti-malaria drug hydroxychloroquine as a potential treatment for the coronavirus.The company is also…

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A box of Plaquenil, an anti-malaria drug hydroxychloroquine made by Sanofi, used for years to treat malaria and autoimmune disorders.

Alain Pitton | NurPhoto | Getty Images

French drugmaker Sanofi said Friday it is suspending recruitment of new patients for its clinical trials looking at anti-malaria drug hydroxychloroquine as a potential treatment for the coronavirus.

The company is also putting a hold on supplying the drug for off-label use to treat Covid-19 until safety concerns are cleared by the World Health Organization.

“Patient safety is Sanofi’s primary focus,” a Sanofi spokesperson said in a statement to CNBC. “In line with WHO’s decision and out of caution, Sanofi has decided to temporarily suspend the recruitment of new patients in both of its clinical trials in COVID-19 patients, pending reassurance on the safety profile of HCQ.”

On Monday, WHO said it temporarily suspended its trial of hydroxychloroquine while the safety data is reviewed by the Data Safety Monitoring Board. The announcement came days after a study published in medical journal The Lancet found that hospitalized Covid-19 patients treated with hydroxychloroquine had a higher risk of death than those who didn’t take it.

Patients who took the drug or chloroquine, which hydroxychloroquine is derived from, were also more likely to develop irregular heart rhythms, according to the study, which looked at more than 96,000 patients from 671 hospitals across six continents. 

Hydroxychloroquine is often used by doctors to treat rheumatoid arthritis and lupus. It is known to have serious side effects, including muscle weakness and heart arrhythmia. 

Even though it isn’t a proven treatment against the coronavirus, doctors can give the drug to patients in a common and legal practice known as “off-label” prescribing. “Off label” means the drug is being used for an ailment not yet approved by the Food and Drug Administration.

Earlier this month, President Donald Trump disclosed he was taking hydroxychloroquine daily to prevent infection from the coronavirus. White House physician Dr. Sean Conley released a memo, which said that after discussing evidence for and against hydroxychloroquine with Trump, they concluded “the potential benefit from treatment outweighed the relative risks.”

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Sanofi can produce up to 600M doses of COVID-19 vaccine https://virusreports.net/sanofi-can-produce-up-to-600m-doses-of-covid-19-vaccine/ https://virusreports.net/sanofi-can-produce-up-to-600m-doses-of-covid-19-vaccine/#respond Sat, 18 Apr 2020 02:21:43 +0000 https://virusreports.net/sanofi-can-produce-up-to-600m-doses-of-covid-19-vaccine/ In an interview, Sanofi (NASDAQ:SNY) chief Paul Hudson said the company can produce up to 600M doses of its coronavirus vaccine next year if studies with partner GlaxoSmithKline (NYSE:GSK) proceed as planned. Clinical trials should launch in H2 with product availability about a year later if all goes well. "We believe that we're one of…

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In an interview, Sanofi (NASDAQ:SNY) chief Paul Hudson said the company can produce up to 600M doses of its coronavirus vaccine next year if studies with partner GlaxoSmithKline (NYSE:GSK) proceed as planned. Clinical trials should launch in H2 with product availability about a year later if all goes well.

“We believe that we’re one of the few companies who will be able to make a vaccine at a huge scale,” he said.

Johnson & Johnson (NYSE:JNJ) stated that it is planning to make 600M – 900M doses of its vaccine by the end of Q1 2021 if its studies proceed as expected.

SNY up 2% premarket while GSK and JNJ are both up 1%, all on light volume.

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