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https://s3.us-west-1.wasabisys.com/virusreports/2020/05/cropped-virus-favicon-32x32.png Fighting Archives - Virus Reports https://virusreports.net/tag/fighting/ 32 32 Fighting Flares Between Azerbaijan and Armenia https://virusreports.net/fighting-flares-between-azerbaijan-and-armenia/ https://virusreports.net/fighting-flares-between-azerbaijan-and-armenia/#respond Sun, 27 Sep 2020 15:21:42 +0000 https://virusreports.net/fighting-flares-between-azerbaijan-and-armenia/ Europe|Fighting Flares Between Azerbaijan and ArmeniaThe governments of both countries reported action with tanks, military helicopters and artillery in a rapid escalation of a long-simmering conflict.A military convoy the disputed mountain enclave of Nagorno-Karabakh in 2017. Fighting between Azerbaijanis and Armenians flared in the region on Sunday.Credit...Celestino Arce/NurPhoto, via Getty ImagesSept. 27, 2020Updated 9:52 a.m. ETMOSCOW —…

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Europe|Fighting Flares Between Azerbaijan and Armenia

The governments of both countries reported action with tanks, military helicopters and artillery in a rapid escalation of a long-simmering conflict.

Credit…Celestino Arce/NurPhoto, via Getty Images

Andrew E. Kramer

MOSCOW — Fighting that was reported to be fierce broke out on Sunday between Azerbaijan and Armenia and quickly escalated with the two sides claiming action with artillery, helicopter and tanks along a disputed border.

The military action centered on the breakaway province of Nagorno-Karabakh, an Armenian separatist enclave in Azerbaijan. Ethnic tensions and historical grievances in the mountainous area north of Turkey and Iran have made kindling for conflict for decades.

The fighting on Sunday, however, was reportedly more severe than the typical periodic border skirmishes, and both governments used military language describing the events as war. Before Sunday, the last major escalation was in 2016. Each sides accused the other of using artillery against civilians.

“The enemy has started an attack” on the Karabakh region, the Armenian prime minister, Nikol Pashinyan, said in a post on Facebook.

Mr. Pashinyan said the military of the Karabkah region, which claims to be an independent state but is mostly unrecognized, had repelled the attack.

But the Ministry of Defense of Azerbaijan then issued a statement saying it had begun a “counterattack” with tanks, helicopters and rocket artillery.

In a statement carried by Russian news agencies, Azerbaijan said the military operation had destroyed “troops, military objects and equipment of the Armenian armed forces” near the border as well as deeper inside the country. It said it destroyed 12 short-range antiaircraft installations in Armenia.

The Armenian Defense Ministry said its forces had destroyed three tanks and shot down two helicopters, Reuters reported.

In past flare-ups, both sides have exaggerated their successes and the scale of their enemies’ violations of cease-fire agreements, though the potential for a wider war has always been clear. The Karabakh region maintains a system to call up nearly its entire male population as minutemen, and this mobilization was announced Sunday morning.

Fighting in and around the Karabakh region, which Armenia calls Artsakh, was among the most vicious of the early post-Soviet conflicts. A cease-fire was declared in 1994, but violence has often flared up since.

Moscow sells weapons to both sides and has also brokered cease-fire agreements. Russia has a military base in Armenia. The Armenian diaspora in France and the United States has aided the Karabakh region, including financing construction of a strategic mountain-access road.

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Gov. Kristi Noem: President Trump is fighting for the common American. He’s fighting for you https://virusreports.net/gov-kristi-noem-president-trump-is-fighting-for-the-common-american-hes-fighting-for-you/ https://virusreports.net/gov-kristi-noem-president-trump-is-fighting-for-the-common-american-hes-fighting-for-you/#respond Thu, 27 Aug 2020 01:21:14 +0000 https://virusreports.net/gov-kristi-noem-president-trump-is-fighting-for-the-common-american-hes-fighting-for-you/ Fox News Back to Top ©2020 FOX News Network, LLC. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed. All market data delayed 20 minutes. New Privacy Policy - New Terms of Use (What's New) - FAQ

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Gym owners on fighting back against shutdown order amid pandemic https://virusreports.net/gym-owners-on-fighting-back-against-shutdown-order-amid-pandemic/ https://virusreports.net/gym-owners-on-fighting-back-against-shutdown-order-amid-pandemic/#respond Sat, 25 Jul 2020 14:21:08 +0000 https://virusreports.net/gym-owners-on-fighting-back-against-shutdown-order-amid-pandemic/ Fox News Back to Top ©2020 FOX News Network, LLC. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed. All market data delayed 20 minutes. New Privacy Policy - New Terms of Use (What's New) - FAQ

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Florida dad is fighting for his life after contracting COVID-19 from his son https://virusreports.net/florida-dad-is-fighting-for-his-life-after-contracting-covid-19-from-his-son/ https://virusreports.net/florida-dad-is-fighting-for-his-life-after-contracting-covid-19-from-his-son/#respond Thu, 16 Jul 2020 23:21:03 +0000 https://virusreports.net/florida-dad-is-fighting-for-his-life-after-contracting-covid-19-from-his-son/ A Florida father is fighting for his life after contracting coronavirus from his son, who tested positive after ignoring his parents' advice to stay home and not gather with friends. John Place, from Plantation, is currently in the intensive care unit at Westside Regional Medical Center where he was put on a ventilator for more than…

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A Florida father is fighting for his life after contracting coronavirus from his son, who tested positive after ignoring his parents’ advice to stay home and not gather with friends. 

John Place, from Plantation, is currently in the intensive care unit at Westside Regional Medical Center where he was put on a ventilator for more than two weeks.  

The 42-year-old and his family all tested positive for COVID-19 last month after his 21-year-old son went out with friends one night and unknowingly brought the respiratory virus back to their home. 

Place however, was the only who required hospitalization after four days of fever and nonstop coughing. He has now been in the hospital for nearly three weeks. 

His wife Michelle Zymet said she had repeatedly pleaded with her stepson, who was not named, to avoid going out with friends and to always wear a mask.  

John Place, 42, from Plantation, Florida has been in the intensive care unit at Westside Regional Medical Center for nearly three weeks after falling seriously ill with COVID-19

Place (far left) and his family all tested positive last month after his 21-year-old son unknowingly brought the virus back to their home after going out with friends 

‘He always assured me, “Don’t worry, mom. I’m doing everything right, relax, chill.” You know how these kids are, so I trusted in him,’ Zymet told 7 News Miami.  

She said she begged him to think about his dad, who is at a higher risk of severe COVID-19 illness because he is overweight and diabetic.

But despite her pleas, he went out against her wishes one night in June, when he gathered with friends and removed his mask while eating and drinking. 

Days later, he felt cold symptoms and a friend at the get-together told him she had tested positive for coronavirus. By then, it already had taken hold in the young man’s household. 

‘You let your guard down just one time, it’s all it takes,’ Zymet added. ‘You come home, and you infect the entire house.’ 

The illness’s spread among members of the family highlights the outcome dreaded by authorities who feared the recent surge of cases hitting younger Floridians would spread to older, more vulnerable people.

‘They don’t necessarily listen. It could be peer pressure,’ Zymet said.

‘Maybe they think, “None of us are sick. We are fine.” They don’t understand many of us are asymptomatic and are positive carriers of the virus.’

Place, who is overweight and diabetic, required hospitalization after four days of fever and nonstop coughing

Zymet’s friends have launched a GoFundMe campaign to raise funds for the family as they brace to handle hefty medical bills

The young man, who did not want to talk to the media, had told his father and stepmother that he initially thought he had a common cold and took over-the-counter medication. 

When he heard about his friend testing positive for coronavirus, he still didn’t think he had it.

But members of the family started to fall ill one by one, starting with his 14-year-old brother, who is also overweight and was wheezing, coughing and lethargic.

The six-year-old sister had only a runny nose. The stepmother was achy, with a fever and chills.  

Zymet and her children have since started to recover from the virus, but her husband remains in serious condition in the ICU. 

With Place unable to work at his photo booth business, Zymet’s friends have launched a GoFundMe campaign to raise funds for the family as they brace to handle hefty medical bills.

Zymet said she has been called an ‘awful mother,’ and an ‘evil witch’ for placing the blame on the stepson, but she said she thought it was important to share her family’s story amid a surge of infections first detected among young people.

Wife Michelle Zymet (left) says she had begged her stepson to be cautious for his father, but he still went out against her wishes 

About 95 percent of hospitals in the City of Miami have reached capacity, Mayor Francis Suarez said on Thursday 

South Florida mayors gathered earlier this week with Florida Gov. Ron DeSantis and told him that gatherings of young people were a key factor in the rise in cases that emerged in June in their region.

Miami-Dade County Mayor Carlos Gimenez said younger people were celebrating the end of school or college, in some cases joining street protests and otherwise just getting together at house parties, underground venues and restaurants that converted themselves into bars late at night in violation of the rules.

With so many close-knit, multigenerational families in the community, spread to older members of families seemed inevitable, he said.

‘Since the young kids started infecting each other, now we see the results as more older folks are now going into the hospital,’ Gimenez said Tuesday. 

‘Exactly what we feared – that they were going to take it to their parents, that they were going to take it to their grandparents.’

On Wednesday, Florida passed the 300,000 mark of confirmed coronavirus cases and has been averaging about 96 deaths per day – more than triple the rate it was about a month ago.

Zymet and her family have been isolating at home, and Place was on a ventilator for more than two weeks. 

She says her stepson has been helping taking care of the younger children and researching the disease while she juggles work in between calls to the hospital, nurses and doctors.

She said the younger generation ‘won’t know until it hits home.’

‘This has definitely brought us together,’ she added. ‘We could have eventually gotten this disease somewhere else. But it is the unfortunate truth that he did bring it home.’

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Trump gave up on fighting the virus. Now we’re paying for his laziness. https://virusreports.net/trump-gave-up-on-fighting-the-virus-now-were-paying-for-his-laziness/ https://virusreports.net/trump-gave-up-on-fighting-the-virus-now-were-paying-for-his-laziness/#respond Tue, 14 Jul 2020 16:21:40 +0000 https://virusreports.net/trump-gave-up-on-fighting-the-virus-now-were-paying-for-his-laziness/ As daily rates of new coronavirus infections surpass 60,000 across the United States, repeatedly shattering single-day records, the Trump administration’s narrative about the virus has shifted. What began as overconfidence intended to downplay epidemiologic data has now turned into fatalism, best captured in the recent Washington Post report that White House officials hope “Americans will…

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As daily rates of new coronavirus infections surpass 60,000 across the United States, repeatedly shattering single-day records, the Trump administration’s narrative about the virus has shifted. What began as overconfidence intended to downplay epidemiologic data has now turned into fatalism, best captured in the recent Washington Post report that White House officials hope “Americans will grow numb to the escalating death toll and learn to accept tens of thousands of new cases a day.” But what remains consistent is a failure by this administration to do the hard work needed to coordinate and orchestrate a federal response, to provide clear risk communication to the public — including, for example, the importance of mask-wearing — and to use emergency powers and flexible resources to support the necessary response to surging case counts. For a pandemic that spreads exponentially, a let-it-play-out approach that accepts mass deaths as inevitable is a disaster for this country and the world.

What is going on? Part of it is a preoccupation with President Trump’s ratings ahead of the November election. Public health experts, for instance, have raised alarm about political interference that removed the Centers for Disease Control and Prevention from leadership in providing clear guidance for reopening and recovery based on data and evidence. Last week, the president tweeted that the CDC’s guidelines for school reopening were “very tough and expensive.” This assessment was followed by confusion: Vice President Pence said revised guidelines would be issued, and a day later, the CDC director, Robert Redfield, backtracked, saying they would remain the same with additional guidance provided.

And as infection rates continue to rise, so has the White House’s search for scapegoats. Managing the administration’s public image appears to be the top priority, never mind that the virus is indifferent to these maneuvers. Trump’s decision to direct full blame at China and the World Health Organization and withdraw from the WHO in the midst of a global pandemic is particularly worrisome. Reports that the administration is deliberating on restructuring the CDC and directing more blame for the crisis there are also troubling at a time when public health officials across the country are being threatened. And the further confirmation that National Institute of Allergy and Infectious Disease Director Anthony S. Fauci’s input is unwanted, as the White House shares with reporters a lengthy list of “mistakes” made in his comments early in the outbreak, adds to a pattern of blaming and redirecting responsibility for the failed response.

Rather than bolstering public health infrastructure, the administration’s approach appears to be to blame, punish and weaken. After months of sacrifice in which Americans were asked to stay home and close businesses to reduce the virus’s spread, the federal government has not ensured that anywhere can reopen safely. Instead, the Trump administration simply decided that it is now time to move on, and that not to do so amounts to taking the “easy way out.” The result is pressure on schools and universities, without the government having done the necessary work to strengthen our public health systems.

To be fair, the erosion of public health infrastructure has occurred across Republican and Democratic administrations, but this time, it seems to be politically motivated. And it raises the question of whether a similar calculus of blame avoidance is the reason for the administration’s refusal to lead a coordinated national response. Rather than serving as a strong partner to local authorities, is it possible that the Trump White House is intentionally shifting responsibility, and therefore blame for any uptick in deaths, to governors? From the beginning, Trump has left states to fend for themselves, and he frequently blames governors — not the lack of a coordinated federal strategy — for the spread of the virus.

An absent federal government means that states and local authorities need to address critical health-care shortages — such as in personal protective equipment and ventilators — on their own, incur tremendous costs in reopening schools safely, and most likely lay off a large number of government workers because there isn’t significant direct aid coming to offset losses in tax and fee revenue. While Congress has enacted some relief laws, including the Cares Act in March, and it’s been supplementing incomes through the Paycheck Protection Program and unemployment insurance, much greater investments are needed. Without an adequate response, individuals and communities that have the money to protect themselves will be able to do so, but the death rates will continue to climb in communities of color and among poorer Americans. Cuts in state budgets will also disproportionately harm those same communities. Already, covid-19 has demonstrated deep racial inequities. So far, excess covid-19 mortality has been borne especially by black, Latino and Native American communities. The decision to persuade the public that we must simply learn to live with thousands of infections each day disregards these inequities about who will be disproportionately harmed. In that way, it isn’t just bad public health; it’s also racist.

Trump’s encouragement of defiance of methods to reduce transmission, from rejecting masks to rushing to reopen without adequate safeguards, has already accelerated the spread of the virus. But as the pandemic sweeps into more rural areas, it is possible that the administration will need to switch tactics and narrative once again. If there is a belief in this White House that the dead won’t be among “our people,” which one wishes was unthinkable, that ultimately will not hold up. The idea that rural and small-town white America is somehow culturally or biologically resistant will falter. Though inequality is racialized in the United States, the same circumstances that create the unfair odds of coronavirus infection — crowded housing, crowded workplaces, inadequate labor protections — also affect many white Americans.

When confronting lethal microbes, humans rely on our wits and capacity to collaborate, as Yale professor Frank Snowden has noted. In quick order after he took office nearly four years ago, Trump dispatched with preparedness. Now, actually faced with a pandemic, he has abandoned any input from scientists. Withdrawal from the WHO removes the United States from the main forum for international cooperation. A federal government that is witless and on its own makes inevitable the grim unfolding scenario.

We hope it won’t take the death toll reaching 200,000 before the administration acknowledges how disastrous the federal response has been and switches tactics. But we fear that only a change in administration can reset our path to recovery.

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Milton teen fighting for her life against COVID-19; family begs people to wear masks https://virusreports.net/milton-teen-fighting-for-her-life-against-covid-19-family-begs-people-to-wear-masks/ https://virusreports.net/milton-teen-fighting-for-her-life-against-covid-19-family-begs-people-to-wear-masks/#respond Mon, 06 Jul 2020 23:21:01 +0000 https://virusreports.net/milton-teen-fighting-for-her-life-against-covid-19-family-begs-people-to-wear-masks/ CLOSE This is how often you should wash your cloth face mask. USA TODAYJust two weeks ago, 16-year-old Halene O'Connell was a normal, healthy teenage girl, ready to start the summer before her senior year at Milton High School. But today, she's in a coma and on a ventilator fighting for her life at the Studer Family…

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This is how often you should wash your cloth face mask.

USA TODAY

Just two weeks ago, 16-year-old Halene O’Connell was a normal, healthy teenage girl, ready to start the summer before her senior year at Milton High School. 

But today, she’s in a coma and on a ventilator fighting for her life at the Studer Family Children’s Hospital at Ascension Sacred Heart in Pensacola, battling a severe case of COVID-19 — and her family is begging the community to wear masks and practice social distancing so they don’t end up in a hospital bed too. 

“We’re very private people, and this is a lot for us to share,” said Carmen Barlianto, Halene’s aunt, in a phone interview from her home in Washington state. “But I feel like we want everybody to know to wear a mask and social distance, so you don’t end up like poor Halene. It can happen to anyone, especially to people her age. Share her story, educate yourself and don’t say this won’t happen to you.”

CDC info: Yes, COVID-19 can be serious for younger adults, too, CDC report shows

A fever and nausea turn into full-blown coronavirus 

Halene has always been healthy and has no underlying health conditions, according to Barlianto, who previously lived in Pensacola for eight years before moving to Washington.

Fourteen days ago, Halene woke up with a fever and nausea. Her parents took her to a doctor, but since she didn’t have shortness of breath —  one of the primary symptoms of coronavirus — she wasn’t immediately tested for COVID-19. 

But within days, her condition began deteriorating rapidly. 

Re-opening woes: Younger people are a factor in surge of COVID-19 cases, analysis shows

“They thought maybe she just had a bug,” Barlianto said. “By that Friday, she couldn’t breathe walking to the bathroom, so they rushed her to the hospital and did testing for COVID, and that’s when they found out she had it.”

Halene was admitted to the Intensive Care Unit on June 28, put in a medically-induced coma and placed on a ventilator. She’s remained there since, and though she’s now in stable condition, she’s still comatose and requires a ventilator to breathe. 

“The thing with this virus is it’s up and down every moment of the day,” Barlianto said, adding that the teen’s fever spiked again on Monday, which the family is hoping is a sign her body is still trying to fight off the virus. 

Due to having been in a coma for so long, it’s unclear what path forward Halene faces if and when she wakes up. At the very least, she’ll need to learn how to breathe, eat and walk on her own again, and doctors aren’t sure yet what the long-term implications could be of both the coma and the virus. 

She could also become diabetic or have blood clots when she recovers, just a few of the side effects of which little is known about the coronavirus. 

“She’s been on the ventilator and sedated for so long, we’re not sure how it’s going to affect her brain,” Barlianto said.

‘COVID just doesn’t care’

It isn’t clear yet where or how Halene initially contracted the virus. 

Barlianto said her sister and family weren’t wearing masks before Halene contracted the disease, though the teen herself wasn’t overly social and wasn’t going out and doing much before she got sick. 

Halene’s mother and father, Robert and Carrie O’Connell, and her 18-year-old sister, Hailey O’Connell, have all since tested negative for the coronavirus. But Robert and Hailey have still quarantined themselves in their Milton home since Halene fell ill, and Carrie has been in the hospital room with her daughter since day one, not allowed to leave. 

“They’ve allowed my sister to stay in the room with her since the first day, however, my sister cannot leave because the room is negative pressure so that COVID air will not be released,” Barlianto said. “My sister has been there the whole time and has not left. They’re feeding her and giving her coloring books, but she has nobody. We’re grateful she’s allowed to be in the room, but I know it’s a daily, minute-by-minute roller coaster ride of stress.”

Doctors are constantly coming in and out and trying to figure out new ways to treat young Halene. The teenage has received plasma from a coronavirus survivor that they’re hopeful will help, and they believe she’s at least halfway through her battle at this point and is on an uphill trend to recovery. 

Masks no more: Milton City Council rescinds mask mandate after public outcry; masks no longer required

Barlianto launched a GoFundMe campaign last week to raise money for her sister’s family since they can’t work at the moment, and since they have “no idea” what the hospital stay will end up costing. 

The family is also asking people to share Halene’s story on social media with the hashtag #MaskForYou, and begging people to wear masks when in public and practice social distancing because her story demonstrates that the virus doesn’t discriminate and can infect anyone. 

Barlianto added that the virus is emotionally taxing on the entire family, as they can’t visit Halene and Carrie in the hospital room, they can’t send flowers and they can’t call her and ask how she’s doing. 

The coronavirus “is nothing like the flu,” Barlianto said, and should be taken more seriously in Florida as it has in Washington state. 

“It’s very confusing. COVID just doesn’t care,” Barlianto said. “It’s like, everybody line up, I’ll take you, let’s take you. It’s just taking random people. It’s not for the sick anymore, it’s not just for the elderly. It’s just attacking anybody at any time.”

Annie Blanks can be reached at ablanks@pnj.com or 850-435-8632. 

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Fighting COVID-19 in Texas as cases spike https://virusreports.net/fighting-covid-19-in-texas-as-cases-spike/ https://virusreports.net/fighting-covid-19-in-texas-as-cases-spike/#respond Thu, 02 Jul 2020 22:21:23 +0000 https://virusreports.net/fighting-covid-19-in-texas-as-cases-spike/ A Texas nurse who says she almost died from COVID-19 returns to the battle lines as doctors voice concerns over the rising number of cases in the state. Jane...

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A Texas nurse who says she almost died from COVID-19 returns to the battle lines as doctors voice concerns over the rising number of cases in the state. Jane…
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How Nurse Fighting COVID-19 Protects Live-in Grandma https://virusreports.net/how-nurse-fighting-covid-19-protects-live-in-grandma/ https://virusreports.net/how-nurse-fighting-covid-19-protects-live-in-grandma/#respond Sat, 30 May 2020 19:21:43 +0000 https://virusreports.net/how-nurse-fighting-covid-19-protects-live-in-grandma/ Nurses all over the world put themselves at risk of contracting the coronavirus by going to work everyday. Its a risk many are willing to take. A nurse in Chicago shows us what a day at the hospital …

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Nurses all over the world put themselves at risk of contracting the coronavirus by going to work everyday. Its a risk many are willing to take. A nurse in Chicago shows us what a day at the hospital …
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T cells play a role in fighting coronavirus; COVID-19 affects children differently https://virusreports.net/t-cells-play-a-role-in-fighting-coronavirus-covid-19-affects-children-differently-2/ https://virusreports.net/t-cells-play-a-role-in-fighting-coronavirus-covid-19-affects-children-differently-2/#respond Mon, 18 May 2020 23:22:40 +0000 https://virusreports.net/t-cells-play-a-role-in-fighting-coronavirus-covid-19-affects-children-differently-2/ By Nancy LapidNEW YORK (Reuters) - The following is a brief roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.Immune system's T cells play a role in attacking the coronavirusWhile the immune system's B cells make antibodies…

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By Nancy Lapid

NEW YORK (Reuters) – The following is a brief roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

Immune system’s T cells play a role in attacking the coronavirus

While the immune system’s B cells make antibodies that block the novel coronavirus, its T cells provide another line of attack, according to new research. Researchers found that T cells from recovered patients can target the virus. That is promising news for vaccine developers because it is “consistent with normal, good, antiviral immunity,” Shane Crotty, from the Center for Infectious Disease and Vaccine Research at the La Jolla Institute for Immunology in California, told Reuters. “The types of immune responses targeted by many candidate vaccines are now shown to be the types of immune responses seen in COVID-19 cases that successfully recovered from the disease.” Furthermore, some people who never had COVID-19 nonetheless had T cells that could attack the virus, Crotty’s team reported on Thursday in the journal Cell. This suggests that past exposure to other coronaviruses (such as those that cause the common cold) had somehow primed their T cells to recognize and attack this new coronavirus. That might influence their susceptibility to COVID-19 disease, he said, either preventing them from getting infected or from developing severe disease. (https://bit.ly/36bRpSD)

Coronavirus affects adults and children differently

Children appear to have much lower rates of infection with the new coronavirus than adults, but most reports on COVID-19 in youngsters have focused only on small groups. A team of Chinese researchers has analyzed data from 24 earlier studies involving a total of nearly 2,600 children with COVID-19, enabling them to shed light on ways in which the virus acts differently in pediatric patients. They reported on Sunday in the Journal of Medical Virology that the most common laboratory test abnormality observed in adults was a low level of immune cells called lymphocytes (B cells and T cells). This condition, known as lymphopenia, developed in up to 80% of adults but in less than 10% of children. On the other hand, children – particularly infants – were more likely to have elevated levels of cardiac enzymes that indicate heart injury. They also found additional differences. The rates of severe illness and critical illness in adults were 14% and 5%, respectively (according to earlier reports). That compared with 4.4% and 0.9% in children. Fever occurred in up to 99% of adults but in 43% of children; cough in up to 82% of adults but 43% of children. Shortness of breath and acute respiratory distress syndrome (ARDS) were rare in children, but digestive tract symptoms like diarrhea were more common in kids than in grownups. (https://bit.ly/3dXpTLf)

Coronavirus can infect patients taking hydroxychloroquine

Taking hydroxychloroquine for other medical conditions might not protect against the new coronavirus, French doctors say. The drug had nearly become a standard of care for patients with COVID-19 in many hospitals, even though randomized trials have not yet confirmed its value. But people around the world use decades-old hydroxychloroquine to treat malaria as well as inflammatory conditions like lupus and rheumatoid arthritis, and researchers are seeing occasional cases of coronavirus infection in these patients despite long-term use of the drug. A report on Sunday in the Journal of Antimicrobial Chemotherapy describes two such patients, one with rheumatoid arthritis and the other with a condition called mixed connectivitis. The authors say they also know of at least three other patients in Italy who became sick with COVID-19 despite taking hydroxychloroquine for chronic arthritis. “Patients actually taking long-term hydroxychloroquine are potentially immunosuppressed patients since they are living with chronic inflammatory diseases and thus do not represent the general population exposed to COVID-19,” the French doctors acknowledge. “However, these observational data are not in favor of a universal protective effect of hydroxychloroquine.” (https://bit.ly/3cDC7bH)

New barcoding technique can help process 100,000 screening tests per day

A big challenge in preventing the spread of the new coronavirus is to identify and quarantine infected people who do not have symptoms. Laboratory workers can test blood samples from thousands of patients per day, still not enough to efficiently screen heavily populated areas. Now researchers at the OSU James Comprehensive Cancer Center in Columbus, Ohio say they have a way to screen over 100,000 samples per day. Their system, dubbed REMBRANDT, makes copies of the virus and introduces two barcodes that simplify patient identification. Barcoding of samples for screening is not new, but the OSU method takes a unique biochemical approach, aiming for a single barcoding and virus-copying step. “Barcodes on products in the supermarket, and molecular barcodes for REMBRANDT work the same way,” investigator Richard Fishel told Reuters. “In this case, each patient has a unique combination of letters that allows for their simplified identification. With ten Next Generation sequencing machines, REMBRANDT can test every Ohio resident for COVID-19 infection every 10 days – an important step in contact tracing and reducing the spread of infection.” His team’s report, published on Sunday on the preprint server bioRxiv, has not yet been peer reviewed. “Our next step,” Fishel said, “will be to collaborate with hospitals and public health departments to clinically validate REMBRANDT and make it available to a wider audience.” (https://bit.ly/2Ax26mT)

GRAPHIC: The lifeline pipeline, COVID-19 treatments, vaccines in development – https://graphics.reuters.com/HEALTH-CORONAVIRUS/yxmvjqywprz/index.html

(Reporting by Nancy Lapid; Editing by Bill Berkrot)

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T cells play a role in fighting coronavirus; COVID-19 affects children differently https://virusreports.net/t-cells-play-a-role-in-fighting-coronavirus-covid-19-affects-children-differently/ https://virusreports.net/t-cells-play-a-role-in-fighting-coronavirus-covid-19-affects-children-differently/#respond Mon, 18 May 2020 21:23:29 +0000 https://virusreports.net/t-cells-play-a-role-in-fighting-coronavirus-covid-19-affects-children-differently/ NEW YORK (Reuters) - The following is a brief roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus. FILE PHOTO: The ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV), which was identified as the cause of…

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NEW YORK (Reuters) – The following is a brief roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

FILE PHOTO: The ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV), which was identified as the cause of an outbreak of respiratory illness first detected in Wuhan, China, is seen in an illustration released by the Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia, U.S. January 29, 2020. Alissa Eckert, MS; Dan Higgins, MAM/CDC/Handout via REUTERS

Immune system’s T cells play a role in attacking the coronavirus

While the immune system’s B cells make antibodies that block the novel coronavirus, its T cells provide another line of attack, according to new research. Researchers found that T cells from recovered patients can target the virus. That is promising news for vaccine developers because it is “consistent with normal, good, antiviral immunity,” Shane Crotty, from the Center for Infectious Disease and Vaccine Research at the La Jolla Institute for Immunology in California, told Reuters. “The types of immune responses targeted by many candidate vaccines are now shown to be the types of immune responses seen in COVID-19 cases that successfully recovered from the disease.” Furthermore, some people who never had COVID-19 nonetheless had T cells that could attack the virus, Crotty’s team reported on Thursday in the journal Cell. This suggests that past exposure to other coronaviruses (such as those that cause the common cold) had somehow primed their T cells to recognize and attack this new coronavirus. That might influence their susceptibility to COVID-19 disease, he said, either preventing them from getting infected or from developing severe disease. (bit.ly/36bRpSD)

Coronavirus affects adults and children differently

Children appear to have much lower rates of infection with the new coronavirus than adults, but most reports on COVID-19 in youngsters have focused only on small groups. A team of Chinese researchers has analyzed data from 24 earlier studies involving a total of nearly 2,600 children with COVID-19, enabling them to shed light on ways in which the virus acts differently in pediatric patients. They reported on Sunday in the Journal of Medical Virology that the most common laboratory test abnormality observed in adults was a low level of immune cells called lymphocytes (B cells and T cells). This condition, known as lymphopenia, developed in up to 80% of adults but in less than 10% of children. On the other hand, children – particularly infants – were more likely to have elevated levels of cardiac enzymes that indicate heart injury. They also found additional differences. The rates of severe illness and critical illness in adults were 14% and 5%, respectively (according to earlier reports). That compared with 4.4% and 0.9% in children. Fever occurred in up to 99% of adults but in 43% of children; cough in up to 82% of adults but 43% of children. Shortness of breath and acute respiratory distress syndrome (ARDS) were rare in children, but digestive tract symptoms like diarrhea were more common in kids than in grownups. (bit.ly/3dXpTLf)

Coronavirus can infect patients taking hydroxychloroquine

Taking hydroxychloroquine for other medical conditions might not protect against the new coronavirus, French doctors say. The drug had nearly become a standard of care for patients with COVID-19 in many hospitals, even though randomized trials have not yet confirmed its value. But people around the world use decades-old hydroxychloroquine to treat malaria as well as inflammatory conditions like lupus and rheumatoid arthritis, and researchers are seeing occasional cases of coronavirus infection in these patients despite long-term use of the drug. A report on Sunday in the Journal of Antimicrobial Chemotherapy describes two such patients, one with rheumatoid arthritis and the other with a condition called mixed connectivitis. The authors say they also know of at least three other patients in Italy who became sick with COVID-19 despite taking hydroxychloroquine for chronic arthritis. “Patients actually taking long-term hydroxychloroquine are potentially immunosuppressed patients since they are living with chronic inflammatory diseases and thus do not represent the general population exposed to COVID-19,” the French doctors acknowledge. “However, these observational data are not in favor of a universal protective effect of hydroxychloroquine.” (bit.ly/3cDC7bH)

New barcoding technique can help process 100,000 screening tests per day

A big challenge in preventing the spread of the new coronavirus is to identify and quarantine infected people who do not have symptoms. Laboratory workers can test blood samples from thousands of patients per day, still not enough to efficiently screen heavily populated areas. Now researchers at the OSU James Comprehensive Cancer Center in Columbus, Ohio say they have a way to screen over 100,000 samples per day. Their system, dubbed REMBRANDT, makes copies of the virus and introduces two barcodes that simplify patient identification. Barcoding of samples for screening is not new, but the OSU method takes a unique biochemical approach, aiming for a single barcoding and virus-copying step. “Barcodes on products in the supermarket, and molecular barcodes for REMBRANDT work the same way,” investigator Richard Fishel told Reuters. “In this case, each patient has a unique combination of letters that allows for their simplified identification. With ten Next Generation sequencing machines, REMBRANDT can test every Ohio resident for COVID-19 infection every 10 days – an important step in contact tracing and reducing the spread of infection.” His team’s report, published on Sunday on the preprint server bioRxiv, has not yet been peer reviewed. “Our next step,” Fishel said, “will be to collaborate with hospitals and public health departments to clinically validate REMBRANDT and make it available to a wider audience.” (bit.ly/2Ax26mT)

GRAPHIC: The lifeline pipeline, COVID-19 treatments, vaccines in development – here

Reporting by Nancy Lapid; Editing by Bill Berkrot

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