{"id":62973,"date":"2020-07-27T21:22:23","date_gmt":"2020-07-27T21:22:23","guid":{"rendered":"https:\/\/virusreports.net\/covid-19-infections-leave-an-impact-on-the-heart-raising-concerns-about-lasting-damage\/"},"modified":"2020-07-27T21:22:23","modified_gmt":"2020-07-27T21:22:23","slug":"covid-19-infections-leave-an-impact-on-the-heart-raising-concerns-about-lasting-damage","status":"publish","type":"post","link":"http:\/\/virusreports.net\/covid-19-infections-leave-an-impact-on-the-heart-raising-concerns-about-lasting-damage\/","title":{"rendered":"COVID-19 infections leave an impact on the heart, raising concerns about lasting damage"},"content":{"rendered":"
\n

This story originally appeared on\u00a0STAT<\/span><\/a>, a health and medicine website that provides ambitious coverage of the coronavirus. Go\u00a0here<\/span><\/a>\u00a0for more stories on the virus. Try\u00a0STAT\u00a0Plus<\/span><\/a>\u00a0for exclusive analysis of biotech, pharma, and the life sciences. And check out STAT\u2019s\u00a0COVID-19 tracker<\/span><\/a>.<\/em><\/p>\n

Two new studies from Germany paint a sobering picture of the toll that Covid-19 takes on the heart, raising the specter of long-term damage after people recover, even if their illness was not severe enough to require hospitalization.<\/p>\n

One study<\/a>\u00a0examined the cardiac MRIs of 100 people who had recovered from Covid-19 and compared them to heart images from 100 people who were similar but not infected with the virus. Their average age was 49 and two-thirds of the patients had recovered at home. More than two months later, infected patients were more likely to have troubling cardiac signs than people in the control group: 78 patients showed structural changes to their hearts, 76 had evidence of a biomarker signaling cardiac injury typically found after a heart attack, and 60 had signs of inflammation.<\/p>\n

These were relatively young, healthy patients who fell ill in the spring, Valentina Puntmann, who led the MRI study, pointed out in an interview. Many of them had just returned from ski vacations. None of them thought they had anything wrong with their hearts.<\/p>\n

\u201cThe fact that 78% of \u2018recovered\u2019 [patients] had evidence of ongoing heart involvement means that the heart is involved in a majority of patients, even if Covid-19 illness does not scream out with the classical heart symptoms, such as anginal chest pain,\u201d she told STAT. She is a cardiologist at University Hospital Frankfurt. \u201cIn my view, the relatively clear onset of Covid-19 illness provides an opportunity to take proactive action and to look for heart involvement early.\u201d<\/p>\n

The\u00a0other study<\/a>, which analyzed autopsy results from 39 people who died early in the pandemic and whose average age was 85, found high levels of the virus in the hearts of 24 patients.<\/p>\n

\u201cWe see signs of viral replication in those that are heavily infected,\u201d Dirk Westermann, a cardiologist at the University Heart and Vascular Centre in Hamburg, said in an interview. \u201cWe don\u2019t know the long-term consequences of the changes in gene expression yet. I know from other diseases that it\u2019s obviously not good to have that increased level of inflammation.\u201d<\/p>\n

Taken together, the two studies, published Monday in JAMA Cardiology, suggest that in many patients, Covid-19 could presage heart failure, a chronic, progressive condition in which the heart\u2019s ability to pump blood throughout the body declines. It is too soon to say if the damage in patients recovering from Covid-19 is transient or permanent, but cardiologists are worried.<\/p>\n

\u201cThese are two studies that both suggest that being infected with Covid-19 carries a high likelihood of having some involvement of the heart. If not answering questions, [they] prompt\u00a0important questions about what the cardiac aftermath is,\u201d said Matthew Tomey, a cardiologist and assistant professor of medicine at the Icahn School of Medicine at Mount Sinai Health System in New York. He was not involved in either study.<\/p>\n

\u201cThe question now is how long these changes persist,\u201d he added. \u201cAre these going to become chronic effects upon the heart or are these \u2014 we hope \u2014\u00a0 temporary effects on cardiac function that will gradually improve over time?\u201d<\/p>\n

Since the pandemic began, people with underlying cardiovascular problems such as high blood pressure, coronary artery disease, or heart failure have been known to be at higher risk for infection and death. The connection between\u00a0Covid-19 and blood clots<\/a>\u00a0emerged later, after doctors began connecting the pulmonary aneurysms, strokes, and heart attacks they were seeing to the virus.<\/p>\n

Cardiac problems in recovering patients could belong to a pattern of\u00a0lingering symptoms<\/a>. Tomey sees signs of weakness in patients who had Covid-19 in March or April, when the disease was surging in New York.<\/p>\n

\u201cPatients come to my office saying, \u2018Hey, I\u2019m a 31-year-old who used to run and be completely unlimited in my exercise, and now I get palpitations walking across the street. Or I get out of breath climbing up to my second-floor apartment,\u2019\u201d he said. \u201cIndividuals are exquisitely tuned in to their own capacity for exercise, so I take that very seriously. Our challenge is to understand the why.\u201d<\/p>\n

Marc Pfeffer, a cardiologist at Brigham and Women\u2019s Hospital in Boston, called both the autopsy and MRI studies\u00a0a sobering warning. He was not involved in either. He\u2019s concerned about relatively young people losing their cardiac health reserves, which typically decrease with age and can set the stage for heart failure.<\/p>\n

\u201cWe knew that this virus, SARS-CoV-2, doesn\u2019t spare the heart,\u201d he said. \u201cWe\u2019re going to get a lot of people through the acute phase [but] I think there\u2019s going to be a long-term price to pay.\u201d<\/p>\n

In an\u00a0editorial<\/a>\u00a0about the two studies, Clyde Yancy, a cardiologist at Northwestern\u2019s Feinberg School of Medicine, and Gregg Fonarow, a cardiologist at UCLA\u2019s Geffen School of Medicine, pushed for more research into the problem.<\/p>\n

\u201cIf this high rate of risk is confirmed, \u2026 then the crisis of COVID-19 will not abate but will instead shift to a new de novo incidence of heart failure and other chronic cardiovascular complications,\u201d they wrote. \u201cWe are inclined to raise a new and very evident concern that cardiomyopathy and heart failure related to Covid-19 may potentially evolve as the natural history of this infection becomes clearer.\u201d<\/p>\n

Asked if there is something that can be done for patients now, Mount Sinai\u2019s Tomey said, \u201cI would love to have the answer to that question.\u201d<\/p>\n

\n<\/hr>\n

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Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

This story originally appeared on\u00a0STAT, a health and medicine website that provides ambitious coverage of the coronavirus. Go\u00a0here\u00a0for more stories on the virus. Try\u00a0STAT\u00a0Plus\u00a0for exclusive analysis of biotech, pharma, and the life sciences. And check out STAT\u2019s\u00a0COVID-19 tracker. Two new studies from Germany paint a sobering picture of the toll that Covid-19 takes on the…<\/p>\n","protected":false},"author":1,"featured_media":62974,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":"","footnotes":""},"categories":[24],"tags":[3,919],"class_list":{"0":"post-62973","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-covid","9":"tag-infections"},"yoast_head":"\nCOVID-19 infections leave an impact on the heart, raising concerns about lasting damage - Virus Reports<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/virusreports.net\/covid-19-infections-leave-an-impact-on-the-heart-raising-concerns-about-lasting-damage\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"COVID-19 infections leave an impact on the heart, raising concerns about lasting damage - Virus Reports\" \/>\n<meta property=\"og:description\" content=\"This story originally appeared on\u00a0STAT, a health and medicine website that provides ambitious coverage of the coronavirus. 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