SummaryBackgroundA vaccine to protect against COVID-19 is urgently needed. We aimed to assess the safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 (Ad5) vectored COVID-19 vaccine expressing the spike glycoprotein of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain.MethodsWe did a dose-escalation, single-centre, open-label, non-randomised, phase 1 trial of an Ad5 vectored COVID-19…
U.S.|Grand Juror in Breonna Taylor Case Says Deliberations Were MisrepresentedThe Kentucky attorney general’s office said it would release the panel’s recordings after a grand juror contended in a court filing that its discussions were inaccurately characterized.Breonna Taylor's family and the lawyer Ben Crump, right, said the charges a Kentucky grand jury agreed upon in the…
(John Finney Photography/Moment/Getty Images) An abnormally bad season of weather may have had a significant impact on the death toll from both World War I and the 1918 Spanish flu pandemic, according to new research, with many more lives being lost due to torrential rain and plummeting temperatures. Through a detailed analysis of an ice…